Derek M. Dykxhoorn : rechercher sur Z-Library

Le plus grand référentiel d'articles scientifiques au monde. 70,000,000+ d'articles gratuitement.

Don't use scam websites

Livres
Articles (43)
Les plus populaires
Liste
- Liste
- Tableau

1

Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors

Song, Erwei, Zhu, Pengcheng, Lee, Sang-Kyung, Chowdhury, Dipanjan, Kussman, Steven, Dykxhoorn, Derek M, Feng, Yi, Palliser, Deborah, Weiner, David B, Shankar, Premlata

Journal:

Nature Biotechnology

Année:

2005

Langue:

english

Fichier:

PDF, 590 KB

english, 2005

2

siRNA-directed inhibition of HIV-1 infection

Novina, Carl D., Murray, Michael F., Dykxhoorn, Derek M., Beresford, Paul J., Riess, Jonathan, Lee, Sang-Kyung, Collman, Ronald G., Lieberman, Judy, Shankar, Premlata, Sharp, Phillip A.

Journal:

Nature Medicine

Année:

2002

Langue:

english

Fichier:

PDF, 456 KB

english, 2002

3

Killing the messenger: short rnas that silence gene expression

Dykxhoorn, Derek M., Novina, Carl D., Sharp, Phillip A.

Journal:

Nature Reviews Molecular Cell Biology

Année:

2003

Langue:

english

Fichier:

PDF, 595 KB

english, 2003

4

Systemic Gene Silencing in Primary T Lymphocytes Using Targeted Lipid Nanoparticles

Ramishetti, Srinivas, Kedmi, Ranit, Goldsmith, Meir, Leonard, Fransisca, Sprague, Andrew G., Godin, Biana, Gozin, Michael, Cullis, Pieter R., Dykxhoorn, Derek M., Peer, Dan

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 4.75 MB

english, 2015

5

Military-related risk factors for dementia

Snyder, Heather M., Carare, Roxana O., DeKosky, Steven T., de Leon, Mony J., Dykxhoorn, Derek, Gan, Li, Gardner, Raquel, Hinds, Sidney R., Jaffee, Michael, Lamb, Bruce T., Landau, Susan, Manley, Geoff

Journal:

Alzheimer's & Dementia

Année:

2018

Langue:

english

Fichier:

PDF, 507 KB

english, 2018

6

Synthesis of the β and β′ subunits of Escherichia coli RNA polymerase is autogenously regulated in vivo by both transcriptional and translational mechanisms

Derek M. Dykxhoorn, Rebecca St. Pierre, Thomas Linn

Journal:

Molecular Microbiology

Année:

1996

Langue:

english

Fichier:

PDF, 445 KB

english, 1996

7

miR-24–mediated downregulation of H2AX suppresses DNA repair in terminally differentiated blood cells

Lal, Ashish, Pan, Yunfeng, Navarro, Francisco, Dykxhoorn, Derek M, Moreau, Lisa, Meire, Eti, Bentwich, Zvi, Lieberman, Judy, Chowdhury, Dipanjan

Journal:

Nature Structural and Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 600 KB

english, 2009

8

Developing a Topical HIV Microbicide: CD4-targeting Aptamers Inhibit HIV Infection in Primary Cells in vitro and in Polarized Human Cervical Explants

Adam Wheeler, Judy Lieberman, Radiana Trifonova, Emre Basar, Derek Dykxhoorn

Journal:

Clinical Immunology

Année:

2010

Langue:

english

Fichier:

PDF, 55 KB

english, 2010

9

RNA interference as an anticancer therapy: a patent perspective

Dykxhoorn, Derek M

Journal:

Expert Opinion on Therapeutic Patents

Année:

2009

Langue:

english

Fichier:

PDF, 475 KB

english, 2009

10

A set of compatible tac promoter expression vectors

Derek M. Dykxhoorn, Rebecca St. Pierre, Thomas Linn

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 333 KB

english, 1996

11

Knocking down Disease with siRNAs

Derek M. Dykxhoorn, Judy Lieberman

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 478 KB

english, 2006

12

Granzyme A Cleaves a Mitochondrial Complex I Protein to Initiate Caspase-Independent Cell Death

Denis Martinvalet, Derek M. Dykxhoorn, Roger Ferrini, Judy Lieberman

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 1.70 MB

english, 2008

13

A PP4-Phosphatase Complex Dephosphorylates γ-H2AX Generated during DNA Replication

Dipanjan Chowdhury, Xingzhi Xu, Xueyan Zhong, Fariyal Ahmed, Jianing Zhong, Ji Liao, Derek M. Dykxhoorn, David M. Weinstock, Gerd P. Pfeifer, Judy Lieberman

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 1.85 MB

english, 2008

14

miR-24 Inhibits Cell Proliferation by Targeting E2F2, MYC, and Other Cell-Cycle Genes via Binding to “Seedless” 3′UTR MicroRNA Recognition Elements

Ashish Lal, Francisco Navarro, Christopher A. Maher, Laura E. Maliszewski, Nan Yan, Elizabeth O'Day, Dipanjan Chowdhury, Derek M. Dykxhoorn, Perry Tsai, Oliver Hofmann, Kevin G. Becker, Myriam Gorospe

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 2.03 MB

english, 2009

15

Derivation of autism spectrum disorder-specific induced pluripotent stem cells from peripheral blood mononuclear cells

Brooke A. DeRosa, Jessica M. Van Baaren, Gaurav K. Dubey, Joycelyn M. Lee, Michael L. Cuccaro, Jeffery M. Vance, Margaret A. Pericak-Vance, Derek M. Dykxhoorn

Journal:

Neuroscience Letters

Année:

2012

Langue:

english

Fichier:

PDF, 977 KB

english, 2012

16

The Silent Revolution: RNA Interference as Basic Biology, Research Tool, and Therapeutic

Dykxhoorn, Derek M., Lieberman, Judy

Journal:

Annual Review of Medicine

Année:

2005

Langue:

english

Fichier:

PDF, 504 KB

english, 2005

17

Target silencing of components of the conserved oligomeric Golgi complex impairs HIV-1 replication

Liu, Sicen, Dominska-Ngowe, Monika, Dykxhoorn, Derek Michael

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 2.22 MB

english, 2014

18

MicroRNAs in Viral Replication and Pathogenesis

Dykxhoorn, Derek M.

Journal:

DNA and Cell Biology

Année:

2007

Langue:

english

Fichier:

PDF, 155 KB

english, 2007

19

RUNNING INTERFERENCE: Prospects and Obstacles to Using Small Interfering RNAs as Small Molecule Drugs

Dykxhoorn, Derek M., Lieberman, Judy

Journal:

Annual Review of Biomedical Engineering

Année:

2006

Langue:

english

Fichier:

PDF, 672 KB

english, 2006

20

Distinct Transcriptomic Features are Associated with Transitional and Mature B-Cell Populations in the Mouse Spleen

Kleiman, Eden, Salyakina, Daria, De Heusch, Magali, Hoek, Kristen L., Llanes, Joan M., Castro, Iris, Wright, Jacqueline A., Clark, Emily S., Dykxhoorn, Derek M., Capobianco, Enrico, Takeda, Akiko, Ren

Journal:

Frontiers in Immunology

Année:

2015

Langue:

english

Fichier:

PDF, 5.10 MB

english, 2015

21

hVGAT-mCherry: A novel molecular tool for analysis of GABAergic neurons derived from human pluripotent stem cells

DeRosa, Brooke A., Belle, Kinsley C., Thomas, Blake J., Cukier, Holly N., Pericak-Vance, Margaret A., Vance, Jeffery M., Dykxhoorn, Derek M.

Journal:

Molecular and Cellular Neuroscience

Année:

2015

Langue:

english

Fichier:

PDF, 2.13 MB

english, 2015

22

RNAi as a potential new therapy for HIV infection

Wheeler, Lee A, Dykxhoorn, Derek M

Journal:

Future HIV Therapy

Année:

2008

Langue:

english

Fichier:

PDF, 1.40 MB

english, 2008

23

C9orf72 promoter hypermethylation is reduced while hydroxymethylation is acquired during reprogramming of ALS patient cells

Esanov, Rustam, Belle, Kinsley C., van Blitterswijk, Marka, Belzil, Veronique V., Rademakers, Rosa, Dickson, Dennis W., Petrucelli, Leonard, Boylan, Kevin B., Dykxhoorn, Derek M., Wuu, Joanne, Benatar

Journal:

Experimental Neurology

Année:

2016

Langue:

english

Fichier:

PDF, 1.04 MB

english, 2016

24

Generation of disease-specific autopsy-confirmed iPSCs lines from postmortem isolated Peripheral Blood Mononuclear Cells

Belle, Kinsley, Shabazz, Francelethia S., Nuytemans, Karen, Davis, David A., Ali, Aleena, Young, Juan L., Scott, William K., Mash, Deborah C., Vance, Jeffrey M., Dykxhoorn, Derek M.

Journal:

Neuroscience Letters

Année:

2016

Langue:

english

Fichier:

PDF, 475 KB

english, 2016

25

MicroRNA-146a Induces Lineage-Negative Bone Marrow Cell Apoptosis and Senescence by Targeting Polo-Like Kinase 2 ExpressionHighlights

Deng, Shanming, Wang, Huilan, Jia, Chunling, Zhu, Shoukang, Chu, Xianming, Ma, Qi, Wei, Jianqin, Chen, Emily, Zhu, Wei, Macon, Conrad J., Jayaweera, Dushyantha T., Dykxhoorn, Derek M., Dong, Chunming

Journal:

Arteriosclerosis Thrombosis and Vascular Biology

Année:

2017

Langue:

english

Fichier:

PDF, 4.36 MB

english, 2017

26

The microRNA -23b/-27b Cluster Suppresses the Metastatic Phenotype of Castration-Resistant Prostate Cancer Cells

Ishteiwy, Reema A., Ward, Toby M., Dykxhoorn, Derek M., Burnstein, Kerry L., Campbell, Moray

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 897 KB

english, 2012

27

ABCA7 FRAMESHIFT DELETION ASSOCIATED WITH ALZHEIMER’S DISEASE IN AFRICAN AMERICANS

Dykxhoorn, Derek M., Cukier, Holly N., Kunkle, Brian W., Vardarajan, Badri N., Rolati, Sophie, Hamilton-Nelson, Kara L., Kohli, Martin A., Whitehead, Patrice L., Van Booven, Derek J., Lang, Rosalyn, F

Journal:

Alzheimer's & Dementia

Année:

2016

Langue:

english

Fichier:

PDF, 58 KB

english, 2016

28

IDENTIFICATION OF NOVEL CANDIDATE GENES FOR EARLY-ONSET ALZHEIMER'S DISEASE THROUGH INTEGRATED WHOLE-EXOME SEQUENCING AND EXOME CHIP ARRAY ASSOCIATION ANALYSIS

Kunkle, Brian W., Vardarajan, Badri N., Naj, Adam C., Cukier, Holly N., Dykxhoorn, Derek M., Rolati, Sophie, Whitehead, Patrice L., Carney, Regina M., Cuccaro, Michael L., Vance, Jeffery M., Genetics

Journal:

Alzheimer's & Dementia

Année:

2016

Langue:

english

Fichier:

PDF, 84 KB

english, 2016

29

A PATIENT-DERIVED IPSC MODEL OF A RARE TTC3 MUTATION

Dykxhoorn, Derek M., Garcia-Serje, Catherine, Johnson, Francelethia of, Carney, Regina, Vance, Jeffery M., Cuccaro, Michael L., Pericak-Vance, Margaret A., Cukier, Holly N.

Journal:

Alzheimer's & Dementia

Année:

2017

Langue:

english

Fichier:

PDF, 165 KB

english, 2017

30

Cocaine Exposure Increases Blood Pressure and Aortic Stiffness via the miR-30c-5p–Malic Enzyme 1–Reactive Oxygen Species Pathway

Zhu, Wei, Wang, Huilan, Wei, Jianqin, Sartor, Gregory C., Bao, Michelle Meiqi, Pierce, Clay T., Wahlestedt, Claes R., Dykxhoorn, Derek M., Dong, Chunming

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 2.02 MB

english, 2018

31

Differentiation of hepatocyte-like cells from human pluripotent stem cells using small molecules

Asumda, Faizal Z., Hatzistergos, Konstantinos E., Dykxhoorn, Derek M., Jakubski, Silvia, Edwards, Jasmine, Thomas, Emmanuel, Schiff, Eugene R.

Journal:

Differentiation

Année:

2018

Langue:

english

Fichier:

PDF, 1.62 MB

english, 2018

32

miR-200 Enhances Mouse Breast Cancer Cell Colonization to Form Distant Metastases

Dykxhoorn, Derek M., Wu, Yichao, Xie, Huangming, Yu, Fengyan, Lal, Ashish, Petrocca, Fabio, Martinvalet, Denis, Song, Erwei, Lim, Bing, Lieberman, Judy, Blagosklonny, Mikhail V.

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 837 KB

english, 2009

33

Complicated Staphylococcus aureus Bacteremia (SAB) Is Associated with Genetic Variation in GLS2

Fowler, Vance, Ruffin, Felicia, Kuinkel, Batu Sharma, Cyr, Derek D, Guo, Shengru, Dykxhoorn, Derek, Skov, Robert, Bruun, Niels, Dahl, Anders, Lærke, Christian, Scott, William, Andersen, Paal

Journal:

Open Forum Infectious Diseases

Année:

2017

Langue:

english

Fichier:

PDF, 71 KB

english, 2017

34

Corrigendum: Distinct Transcriptomic Features Are Associated with Transitional and Mature B-Cell Populations in the Mouse Spleen

Kleiman, Eden, Salyakina, Daria, De Heusch, Magali, Hoek, Kristen L., Llanes, Joan M., Castro, Iris, Wright, Jacqueline A., Clark, Emily S., Dykxhoorn, Derek M., Capobianco, Enrico, Takeda, Akiko, McC

Journal:

Frontiers in Immunology

Année:

2016

Langue:

english

Fichier:

PDF, 92 KB

english, 2016

35

Human genetic variation in GLS2 is associated with development of complicated Staphylococcus aureus bacteremia

Scott, William K., Medie, Felix Mba, Ruffin, Felicia, Sharma-Kuinkel, Batu K., Cyr, Derek D., Guo, Shengru, Dykxhoorn, Derek M., Skov, Robert L., Bruun, Niels E., Dahl, Anders, Lerche, Christian J., P

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 1.76 MB

english, 2018

36

LDL Cholesterol Uptake Assay Using Live Cell Imaging Analysis with Cell Health Monitoring

Ritter, Portia, Yousefi, Keyvan, Ramirez, Juliana, Dykxhoorn, Derek M., Mendez, Armando J., Shehadeh, Lina A.

Journal:

Journal of Visualized Experiments

Année:

2018

Langue:

english

Fichier:

PDF, 2.18 MB

english, 2018

37

Blood Derived Induced Pluripotent Stem Cells (iPSCs): Benefits, Challenges and the Road Ahead

Hokayem, Jimmy El, Cukier, Holly N, Dykxhoorn, Derek M

Journal:

Journal of Alzheimer's Disease & Parkinsonism

Année:

2016

Langue:

english

Fichier:

PDF, 789 KB

english, 2016

38

HIV and HCV augments inflammatory responses through increased TREM-1 expression and signaling in Kupffer and Myeloid cells

Hyun, Jinhee, McMahon, Robert S., Lang, Anna L., Edwards, Jasmine S., Badilla, Alejandro Dmitar, Greene, Morgan E., Stone, Geoffrey W., Pallikkuth, Suresh, Stevenson, Mario, Dykxhoorn, Derek M., Kotti

Journal:

Année:

2019

Langue:

english

Fichier:

PDF, 5.96 MB

english, 2019

39

MITIGATING COMPLEXITIES IN RECRUITING AND RETAINING AFRICAN AMERICAN (AA) MULTIPLEX FAMILIES FOR ALZHEIMER DISEASE RESEARCH

Starks, Takiyah D., Byfield, Grace, Naney, Kristen B., Luther, Ronqeiya, King, Vivian, Dykxhoorn, Derek M., Cukier, Holly N., Edwards, Christopher, Adams, Larry D., Haines, Jonathan L., Cuccaro, Micha

Journal:

Alzheimer's & Dementia

Année:

2019

Langue:

english

Fichier:

PDF, 738 KB

english, 2019

40

Three Brothers With Autism Carry a StopâGain Mutation in the HPAâAxis Gene NR3C2

Cukier, Holly N., Griswold, Anthony J., Hofmann, Natalia K., Gomez, Lissette, Whitehead, Patrice L., Abramson, Ruth K., Gilbert, John R., Cuccaro, Michael L., Dykxhoorn, Derek M., PericakâVance, Mar

Journal:

Autism Research

Année:

2020

Fichier:

PDF, 252 KB

2020

41

P3-206: INVESTIGATING ANCESTRY SPECIFIC DIFFERENCES IN APOE FUNCTION USING INDUCED PLURIPOTENT STEM CELLS

Dykxhoorn, Derek M., Cukier, Holly N., Maddy, Krisna S., Adams, Larry D., Starks, Takiyah D., Celis, Katrina, Acosta, Heriberto, Feliciano-Astacio, Briseida E., Byrd, Goldie S., Cuccaro, Michael L., B

Journal:

Alzheimer's & Dementia

Année:

2019

Fichier:

PDF, 166 KB

2019

42

UTILIZING CRISPR TO INVESTIGATE AN ETHNIC SPECIFIC DELETION IN ABCA7

Cukier, Holly N., Nuytemans, Karen, Strong, Thomas A., Laverde-Paz, Juliana, Eldabbas, Rawan A., Pericak-Vance, Margaret A., Dykxhoorn, Derek M.

Journal:

Alzheimer's & Dementia

Année:

2019

Fichier:

PDF, 168 KB

2019

43

Characterization of UMi028-A-1 stem cell line that contains a CRISPR/Cas9 induced hearing loss-associated variant (V60L (c.178GÂ >Â T)) in the P2RX2 gene

Gosstola, Nicholas C., Huang, Zaohua, Tong, Xiaoying, Nourbakhsh, Aida, Chen, Zheng-Yi, Dykxhoorn, Derek M., Zhong Liu, Xue

Journal:

Stem Cell Research

Année:

2020

Fichier:

PDF, 2.20 MB

2020